Expression and clinical correlation of cathepsin S, programmed cell death-1 ligand 1, and BRAFV600E mutation in children with Langerhans cell histiocytosis
CTSS is positively expressed in LCH, and its expression level is associated with onset age ≤ 2 years. BRAFV600E gene mutation, PD-L1, and CTSS may not be associated with the prognosis of LCH.
Authors
- Shihong Shao (ORCID: https://orcid.org/0000-0003-2013-7752)
- Lingzhen Wang
- Lirong Sun (ORCID: https://orcid.org/0000-0002-5035-7601)
- Yongan Ni (ORCID: https://orcid.org/0000-0003-0793-7093)
- Yilin Wang
Institutions
- Qingdao University (CN)
- Affiliated Hospital of Qingdao University (CN)
Publication Details
- Journal
- The Turkish Journal of Pediatrics
- Published
- 2025-09-01
- DOI
- https://doi.org/10.24953/turkjpediatr.2025.5882
- Primary Topic
- Histiocytic Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00