Secondary Choroidal Osteoma in the Setting of Uveal Pathology: 4 Case Reports and Review
We observed 5 eyes of four patients with choroidal osteoma in the choriocapillaris and Sattler's layer of the choroid secondary to CSCR, Vogt-Koyanagi-Harada disease, or posterior scleritis over a long follow-up period of 12-30 years. Secondary choroidal osteoma, ectopic bone in the choroid, can result from the transformation of mesenchymal cells stimulated by osteoprogenitors, such as bone morphogenetic proteins. Secondary choroidal osteoma should be recognized as a rare long-term complication of uveal pathologies.
Authors
- Carol L. Shields (ORCID: https://orcid.org/0000-0002-3288-3632)
- Minoru Furuta (ORCID: https://orcid.org/0000-0003-2193-8279)
- Tetsuju Sekiryu (ORCID: https://orcid.org/0000-0001-8042-2729)
- Ryo Mukai (ORCID: https://orcid.org/0000-0003-1796-9232)
- Shunsuke Maeda
- Keiichiro Tanaka (ORCID: https://orcid.org/0000-0002-6315-2269)
- Jerry A. Shields
Institutions
- Fukushima Medical University (JP)
- Thomas Jefferson University (US)
- Soma Central Hospital (JP)
- Wills Eye Hospital (US)
Publication Details
- Journal
- Ocular Oncology and Pathology
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1159/000548250
- Primary Topic
- Ocular Oncology and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00