Prevalence, Clinical Characteristics, and Mortality Impact of Metallo-β-Lactamase-Producing Enterobacter Cloacae Complex Infections: A Retrospective Cohort Study
MBL-producing ECC infections are associated with high antibiotic resistance, increased healthcare resource utilisation, and significantly higher mortality, particularly in bloodstream infections. The predominance of bla<sub>NDM</sub> among MBL genes aligns with recent regional trends. These findings underscore the urgent need for enhanced surveillance, rapid diagnostics, and targeted management strategies to address this emerging threat.
Authors
- Yi-Pei Lee
- Yu-Chieh Liao (ORCID: https://orcid.org/0000-0002-4360-7932)
- Feng-Jui Chen (ORCID: https://orcid.org/0000-0003-2270-2591)
- Po‐Yu Liu (ORCID: https://orcid.org/0000-0001-8006-4917)
- Ting-Wei Lin
- Hsien-Po Huang (ORCID: https://orcid.org/0009-0005-8697-1047)
- Hui‐Hsien Pan
Institutions
- National Chung Hsing University (TW)
- National Health Research Institutes (TW)
- Taichung Veterans General Hospital (TW)
- Chung Shan Medical University Hospital (TW)
Publication Details
- Journal
- Journal of Global Antimicrobial Resistance
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1016/j.jgar.2025.08.014
- Citations
- 3
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 1.77
Funders
- Taichung Veterans General Hospital