Impact of Progression Sites and Line of Therapy on Survival Outcomes in Patients with Her-2 Positive Metastatic Breast Cancer Treated with T-DM1
Progression to brain and lung during T-DM1 treatment correlates with higher mortality. Early-line use of T-DM1 may be linked with worse outcomes, possibly due to more aggressive disease biology. The obtained data could inform the decision-making process when treating patients with HER2+ MBC and predict their prognosis.
Authors
- Heves Sürmeli (ORCID: https://orcid.org/0000-0003-1604-8466)
Institutions
- Dr Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi (TR)
- Sağlık Bilimleri Üniversitesi (TR)
Publication Details
- Journal
- Northern Clinics of Istanbul
- Published
- 2025-01-01
- DOI
- https://doi.org/10.14744/nci.2025.48902
- Primary Topic
- Advanced Breast Cancer Therapies
- Type
- article
- Field-Weighted Citation Impact
- 0.00