Age and Clinical Activity Score (CAS): Key Predictive Factors for Non-shrinking Extraocular Muscles in Graves’ Ophthalmopathy After Retrobulbar Injection of Glucocorticoids (GCs)

Age and disease activity (CAS≥3) are significant predictors of non-shrinking EOMs after retrobulbar GCs injection in GO patients. These findings can help clinicians better assess treatment outcomes and optimize therapeutic strategies for GO patients. Future research should focus on expanding the sample size and exploring underlying biological mechanisms to further validate these findings and improve treatment precision.

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Publication Details

Journal
Cureus
Published
2025-08-31
DOI
https://doi.org/10.7759/cureus.91353
Primary Topic
Ophthalmology and Eye Disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

Age and Clinical Activity Score (CAS): Key Predictive Factors for Non-shrinking Extraocular Muscles in Graves’ Ophthalmopathy After Retrobulbar Injection of Glucocorticoids (GCs)

Yuying Xiang, Rui Li, Guang Zhao, Junjie Yang et al.
Cureus
Ophthalmology and Eye Disorders
article

Age and Clinical Activity Score (CAS): Key Predictive Factors for Non-shrinking Extraocular Muscles in Graves’ Ophthalmopathy After Retrobulbar Injection of Glucocorticoids (GCs)

Yuying Xiang, Rui Li, Guang Zhao, Junjie Yang, Fagang Jiang
article en

Abstract

Age and disease activity (CAS≥3) are significant predictors of non-shrinking EOMs after retrobulbar GCs injection in GO patients. These findings can help clinicians better assess treatment outcomes and optimize therapeutic strategies for GO patients. Future research should focus on expanding the sample size and exploring underlying biological mechanisms to further validate these findings and improve treatment precision.

CureusVol. 17(8)
Wuhan Union Hospital (CN), Huazhong University of Science and Technology (CN)
Moonshot Research and Development Program
Openalex Percentile: Top 67%
Ophthalmology and Eye Disorders
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