Mandibular osteomyelitis in a rheumatoid arthritis patient with chronic prednisolone abuse: A case report

Mandibular osteomyelitis is a severe inflammatory condition affecting the jawbone, often linked to chronic infections and immunosuppression. This case report highlights a 35-year-old female with rheumatoid arthritis who developed mandibular osteomyelitis with a parotid abscess following prolonged corticosteroid use without medical supervision. Clinical evaluation revealed multiple draining sinuses, facial swelling, and trismus. Imaging confirmed an ill-defined lobulated soft tissue lesion involving the right parotid gland with cortical erosion of the mandible. Laboratory findings indicated anemia and neutrophilia, while culture showed no growth. The patient was treated with antibiotic therapy, steroid tapering, and supportive care. This case underscores the role of long-term corticosteroid abuse as a significant risk factor for osteomyelitis, emphasizing the need for monitoring steroid dosage, patient education, and regular follow-up to prevent severe complications.

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Publication Details

Journal
International Journal of Pharmacology and Clinical Research
Published
2025-01-01
DOI
https://doi.org/10.33545/26647613.2025.v7.i2b.100
Primary Topic
Osteomyelitis and Bone Disorders Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Mandibular osteomyelitis in a rheumatoid arthritis patient with chronic prednisolone abuse: A case report

Paramasivam Deepak, Jayashree Nagaral, Sahana GN, Ganavi MV
International Journal of Pharmacology and Clinical Research
Osteomyelitis and Bone Disorders Research
article

Mandibular osteomyelitis in a rheumatoid arthritis patient with chronic prednisolone abuse: A case report

Paramasivam Deepak, Jayashree Nagaral, Sahana GN, Ganavi MV
article en

Abstract

Mandibular osteomyelitis is a severe inflammatory condition affecting the jawbone, often linked to chronic infections and immunosuppression. This case report highlights a 35-year-old female with rheumatoid arthritis who developed mandibular osteomyelitis with a parotid abscess following prolonged corticosteroid use without medical supervision. Clinical evaluation revealed multiple draining sinuses, facial swelling, and trismus. Imaging confirmed an ill-defined lobulated soft tissue lesion involving the right parotid gland with cortical erosion of the mandible. Laboratory findings indicated anemia and neutrophilia, while culture showed no growth. The patient was treated with antibiotic therapy, steroid tapering, and supportive care. This case underscores the role of long-term corticosteroid abuse as a significant risk factor for osteomyelitis, emphasizing the need for monitoring steroid dosage, patient education, and regular follow-up to prevent severe complications.

International Journal of Pharmacology and Clinical ResearchVol. 7(2)
Openalex Percentile: Top 65%
Osteomyelitis and Bone Disorders Research
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Mandibular osteomyelitis in a rheumatoid arthritis patient with chronic prednisolone abuse: A case report — Paramasivam Deepak, Jayashree Nagaral, et al. · International Journal of Pharmacology and Clinical Research (2025) | TGRS Research Map | TGRS