A Study of Dosimetric Feasibility of a New Approach of Radiosurgery for Multiple Sclerosis-Related Trigeminal Neuralgia

The double-isocenter technique effectively expanded nerve coverage without compromising brainstem safety, as the brainstem Dmax remained within acceptable limits. Although the increase in brainstem V(10Gy) was statistically significant, its absolute value remained well below established tolerance guidelines, suggesting that the clinical impact is likely negligible. This approach demonstrates feasibility and supports future clinical trials to evaluate efficacy and long-term outcomes in MS-TN patients.