Gradient Myopic Defocus Causes Chick Scleral Tissue Reinforcement and Structural Scleral Remodeling

It is possible to induce appositional growth in hyaline cartilage in the chick sclera. In our study, this has only been achieved by using MPC lenses to reverse previously induced experimental myopia with conventional minus lenses. Our findings suggest that a gradient decrease in peripheral lens power and the resulting differential defocus could trigger of scleral reinforcement through of cartilage growth stimulation in the chick sclera.