Acute cutaneous adverse drug reactions in hepatocellular carcinoma patients undergoing combined targeted and immunotherapy: unraveling the impact of dosage and interval
In HCC patients receiving combined regimens, atypical targetoid rashes indicate a more severe CADR. Full-dose targeted agents and shorter intervals between targeted agents and ICIs may contribute to the more severe CADR phenotype.
Authors
- Tong Li (ORCID: https://orcid.org/0000-0002-1748-6030)
- Kefei Chen (ORCID: https://orcid.org/0000-0002-2380-3805)
- Jingyi Li (ORCID: https://orcid.org/0000-0001-6822-7998)
- Li Xu (ORCID: https://orcid.org/0000-0003-1709-2485)
- Lin Li (ORCID: https://orcid.org/0000-0001-8852-8122)
- Bo Li (ORCID: https://orcid.org/0000-0001-6364-8574)
- Yonggang Wei (ORCID: https://orcid.org/0000-0002-1411-3722)
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
Publication Details
- Journal
- Cutaneous and Ocular Toxicology
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1080/15569527.2025.2552715
- Citations
- 1
- Primary Topic
- Drug-Induced Adverse Reactions
- Type
- article
- Field-Weighted Citation Impact
- 1.39