Mapping DWI signal reversal and long-term tissue outcomes following endovascular therapy in acute ischemic stroke
Question Understanding diffusion-weighted imaging reversal following endovascular therapy is crucial for stroke diagnostics, yet its regional distribution and long-term tissue-specific consequences remain poorly characterized. Findings Diffusion-weighted imaging reversal occurred throughout the brain, often persisted, and did not significantly differ between white matter and cortical regions. Clinical relevance Restrictive diffusion on MRI should be used with caution to exclude acute ischemic stroke patients from endovascular therapy, as such changes often respond to treatment both in white and gray matter.
Authors
- Brian Enriquez (ORCID: https://orcid.org/0000-0002-6535-0445)
- Anne Hege Aamodt (ORCID: https://orcid.org/0000-0002-2824-2760)
- Jonathan Frederik Carlsen (ORCID: https://orcid.org/0000-0002-6724-7281)
- Cecilie Mørck Offersen (ORCID: https://orcid.org/0000-0001-5763-6892)
- Kine Mari Bakke (ORCID: https://orcid.org/0000-0003-2127-752X)
- Atle Bjørnerud (ORCID: https://orcid.org/0000-0002-3486-3141)
- Mona K. Beyer
- Terje Nome (ORCID: https://orcid.org/0000-0003-1779-3054)
- Thor Håkon Skattør (ORCID: https://orcid.org/0000-0002-6746-1579)
Institutions
- University of Copenhagen (DK)
- Oslo University Hospital (NO)
- University of Oslo (NO)
- Norwegian University of Science and Technology (NO)
- Copenhagen University Hospital (DK)
- Rigshospitalet (DK)
Publication Details
- Journal
- European Radiology
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1007/s00330-025-11943-0
- Citations
- 1
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- Universitetet i Oslo
- Helse Sør-Øst RHF