Multivessel Spontaneous Coronary Artery Dissection and Myocarditis: A Rare Case Highlighting the Value of Multimodality Cardiac Imaging

Spontaneous coronary artery dissection (SCAD), once considered too rare to study, is now recognized as an important nonatherosclerotic and nontraumatic cause of myocardial infarction, especially in young women. However, it is often challenging to differentiate from alternative etiologies of chest discomfort, such as atherosclerotic acute coronary syndromes or myocarditis. Here, we describe the unique case of a young woman who presented with an acute chest pain syndrome and was found to have co-occurring myocarditis and multivessel SCAD. The use of multimodality imaging studies to include transthoracic echocardiogram (TTE), cardiac magnetic resonance imaging (MRI), coronary computed tomography angiography (CCTA), invasive coronary angiography (ICA), and intravascular ultrasound (IVUS) delivered the confirmation of concomitant diagnoses which were consistent with the clinical presentation. This case highlights the critical role of multimodality imaging in the diagnosis and management of coexistent cardiac pathologies.

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Publication Details

Journal
Cureus
Published
2025-09-01
DOI
https://doi.org/10.7759/cureus.91407
Primary Topic
Cardiovascular Issues in Pregnancy
Type
article
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0.00
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article

Multivessel Spontaneous Coronary Artery Dissection and Myocarditis: A Rare Case Highlighting the Value of Multimodality Cardiac Imaging

Matthew Tunzi, John-Henry L Dean, Rosco Gore, Jared C Daddario
Cureus
Cardiovascular Issues in Pregnancy
article

Multivessel Spontaneous Coronary Artery Dissection and Myocarditis: A Rare Case Highlighting the Value of Multimodality Cardiac Imaging

Matthew Tunzi, John-Henry L Dean, Rosco Gore, Jared C Daddario
article en

Abstract

Spontaneous coronary artery dissection (SCAD), once considered too rare to study, is now recognized as an important nonatherosclerotic and nontraumatic cause of myocardial infarction, especially in young women. However, it is often challenging to differentiate from alternative etiologies of chest discomfort, such as atherosclerotic acute coronary syndromes or myocarditis. Here, we describe the unique case of a young woman who presented with an acute chest pain syndrome and was found to have co-occurring myocarditis and multivessel SCAD. The use of multimodality imaging studies to include transthoracic echocardiogram (TTE), cardiac magnetic resonance imaging (MRI), coronary computed tomography angiography (CCTA), invasive coronary angiography (ICA), and intravascular ultrasound (IVUS) delivered the confirmation of concomitant diagnoses which were consistent with the clinical presentation. This case highlights the critical role of multimodality imaging in the diagnosis and management of coexistent cardiac pathologies.

CureusVol. 17(9)
San Antonio Uniformed Services Health Education Consortium (US)
Openalex Percentile: Top 64%
Cardiovascular Issues in Pregnancy
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Multivessel Spontaneous Coronary Artery Dissection and Myocarditis: A Rare Case Highlighting the Value of Multimodality Cardiac Imaging — Matthew Tunzi, John-Henry L Dean, et al. · Cureus (2025) | TGRS Research Map | TGRS