Advantages and disadvantages of various methods for diagnosing intestinal microbiota disorders

The article explores modern methods for diagnosing gut microbiota disorders, including cultural, molecular-genetic, and chromatographic approaches. Their advantages, disadvantages, and clinical significance are highlighted. A significant milestone was the adoption of the international consensus standardizing microbiome diagnostic practices. The article emphasizes the need to select diagnostic methods based on research goals and clinical conditions, considering accuracy, availability, and cost.

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Publication Details

Journal
Experimental and Clinical Gastroenterology
Published
2025-08-31
DOI
https://doi.org/10.31146/1682-8658-ecg-234-2-179-186
Primary Topic
Clostridium difficile and Clostridium perfringens research
Type
article
Field-Weighted Citation Impact
0.00
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article

Advantages and disadvantages of various methods for diagnosing intestinal microbiota disorders

K. N. Nadzhafova, Yu. A. Fominykh, M. . Ogay
Experimental and Clinical Gastroenterology
Clostridium difficile and Clostridium perfringens research
article

Advantages and disadvantages of various methods for diagnosing intestinal microbiota disorders

K. N. Nadzhafova, Yu. A. Fominykh, M. . Ogay
article en

Abstract

The article explores modern methods for diagnosing gut microbiota disorders, including cultural, molecular-genetic, and chromatographic approaches. Their advantages, disadvantages, and clinical significance are highlighted. A significant milestone was the adoption of the international consensus standardizing microbiome diagnostic practices. The article emphasizes the need to select diagnostic methods based on research goals and clinical conditions, considering accuracy, availability, and cost.

Experimental and Clinical Gastroenterology(2)
Federal Almazov North-West Medical Research Centre (RU), Ministry of Health of the Russian Federation (RU), Saint Petersburg State Pediatric Medical University (RU)
Openalex Percentile: Top 72%
Clostridium difficile and Clostridium perfringens research
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