A novel SWI/SNF complex promotes triple-negative breast cancer progression
This research enhances the understanding of the intricate roles played by SWI/SNF complex components in TNBC and bridges the gap between the structural specificity of SWI/SNF assembly and the progression of cancer. These findings could potentially unveil novel therapeutic targets for TNBC, thereby advancing the development of more efficacious treatment approaches for this highly aggressive malignancy.
Authors
- Qunxing Huang (ORCID: https://orcid.org/0000-0002-7328-111X)
- Wenyi Sheng (ORCID: https://orcid.org/0000-0002-4926-0060)
- Huanhuan Huang (ORCID: https://orcid.org/0000-0003-0845-7526)
- Meng You (ORCID: https://orcid.org/0000-0001-6189-1845)
- Shiqi Liu (ORCID: https://orcid.org/0000-0002-6690-9896)
- Weifeng Qian
- Wen‐Jie Wang (ORCID: https://orcid.org/0000-0002-5214-1476)
- Yue Zhu (ORCID: https://orcid.org/0000-0003-2490-6029)
- Cheng Jian-xi
Institutions
- Suzhou Municipal Hospital (CN)
Publication Details
- Journal
- Cellular & Molecular Biology Letters
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1186/s11658-025-00788-6
- Citations
- 1
- Primary Topic
- Chromatin Remodeling and Cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Suzhou Municipal Health Commission
- National Natural Science Foundation of China
- Natural Science Foundation of Jiangsu Province
- Suzhou Municipal Science and Technology Bureau