Dynamic TyG–inflammation–endothelial trajectories and placental histopathology synergistically define a maternal–fetal vascular risk phenotype

Placental vascular and inflammatory lesions potentiate the impact of adverse maternal metabolic inflammatory trajectories on fetal arterial remodeling. Integrating rapid placental histology with dynamic TyG inflammation endothelial indices could refine perinatal risk stratification and guide both ante and postpartum surveillance.