Treatment outcomes and associated influencing factors among elderly patients with rifampicin-resistant tuberculosis: a multicenter, retrospective, cohort study in China
A relatively low rates of treatment success were achieved for RR-TB patients in the elderly at tertiary tuberculosis hospitals in China. Low BMI, advanced drug resistance, and pre-treatment anemia were independent prognostic factors for unfavorable treatment outcomes. Adjunctive immunotherapy was prognostic factors for unfavorable treatment outcomes of elderly RR-TB patients. In tuberculosis management, special consideration should be given to elderly patients.
Authors
- Wanli Kang (ORCID: https://orcid.org/0000-0002-3329-7096)
- Qing Pan (ORCID: https://orcid.org/0000-0002-4372-5349)
- Qing Chen (ORCID: https://orcid.org/0000-0003-4108-7977)
- Li‐Ping Zou (ORCID: https://orcid.org/0000-0001-7233-9378)
- Yang Song (ORCID: https://orcid.org/0000-0002-2454-8498)
- Shenjie Tang (ORCID: https://orcid.org/0000-0002-9131-4165)
- Zhouli Guo
- Peijun Tang (ORCID: https://orcid.org/0000-0002-8967-8568)
- Zhengyu Shi
- Huicong Liu (ORCID: https://orcid.org/0000-0003-3651-9114)
- Liang Li (ORCID: https://orcid.org/0000-0002-0781-9735)
- Juan Du (ORCID: https://orcid.org/0009-0001-0314-630X)
- Jiaojie Ma
- Qingdong Zhu (ORCID: https://orcid.org/0009-0003-3368-5296)
- Jiajia Yu (ORCID: https://orcid.org/0009-0002-8619-4784)
- Xianzhen Tang
- Chunhui Guo
- Guihui Wu
- Zhanlin Chang
Institutions
- Army Medical University (CN)
- Capital Medical University (CN)
- Beijing Chao-Yang Hospital, Capital Medical University (CN)
- Soochow University (CN)
- The Fourth People's Hospital (CN)
- Beijing Chest Hospital (CN)
- Heilongjiang Center for Tuberculosis Control and Prevention (CN)
- Wuhan Pulmonary Hospital (CN)
- Southwest Hospital (CN)
- Tibet Autonomous Region People's Hospital (CN)
- Anqing City Hospital (CN)
- Public Health Clinical Center of Chengdu (CN)
- The Fifth People’s Hospital of Suzhou (CN)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1186/s12879-025-11491-4
- Citations
- 2
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 2.79
Funders
- Department of Science and Technology of Sichuan Province
- National Key Research and Development Program of China