Periodontal Health in Pregnant Women with and without Intrahepatic Cholestasis of Pregnancy: A Comparative Study

symptoms disappear rapidly and her blood liver test values return to normal. 13,14Regarding our poor understanding of the etiology of IHCP, there is still dispute.Chronic periodontitis is a complex disease that can progress unexpectedly and causes inflammation and the degeneration of supporting tissues.The concept of periodontal disease has changed from being one of a slowly progressing illness to one of attachment loss that happens in sporadic bursts. 15,16ALP, a membranebound glycoprotein, is manufactured by leukocytes, osteoblasts, IntroductIonIntrahepatic cholestasis of pregnancy (IHCP) is an intrahepatic condition that affects pregnant females in the second or third trimester of pregnancy.This disorder is characterized by raised counts of bile acids, a feeling of itching or pruritus, and considerable levels of high serum aminotransferases. 1,2These symptoms, however, are resolved after 2-3 weeks postpartum.The first recorded case of the aforementioned malady was reported by Ahlfeld in 1883. 3he sense of itching or pruritus is a primary symptom that is observed in a pregnant female in the second or third trimester of pregnancy.The discomfort varies from patient to patient.Some experience mild and manageable discomfort, but for some, it can be debilitating. 4,5he symptom of pruritus most often occurs during the evenings and severely affects the palms and the soles of the feet.This sensation, however, does not correlate with any specific skin lesion. 4,6,7Generally occurring in the third trimester, after approximately 30 weeks of gestation, there have been rare reports of it appearing as early as 6-10 weeks. 8,9Ten to fifteen percent of people with slightly elevated conjugated bilirubin levels in their serum exhibit mild jaundice. 10Serum alkaline phosphatase (ALP) levels can increase to 7-10 times normal in response to elevated placenta isoenzyme, which complicates interpretation. 11,12The mother's prognosis is good because, following delivery, her