Reduction of supervision for biomedical knowledge discovery

Our approach tackles a central issue in knowledge discovery: balancing performance with minimal supervision which is crucial to adapting models to varied and changing domains. This study also investigates the use of pointwise binary classification techniques within a weakly supervised framework for knowledge discovery. By gradually decreasing supervision, we assess the robustness of these techniques in handling noisy labels, revealing their capability to shift from weakly supervised to entirely unsupervised scenarios. Comprehensive benchmarking offers insights into the effectiveness of these techniques, examining how unsupervised methods can reliably capture complex relationships in biomedical texts. These results suggest an encouraging direction toward scalable, adaptable knowledge discovery systems, representing progress in creating data-efficient methodologies for extracting useful insights when annotated data is limited.

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Publication Details

Journal
BMC Bioinformatics
Published
2025-09-01
DOI
https://doi.org/10.1186/s12859-025-06187-0
Primary Topic
Biomedical Text Mining and Ontologies
Type
article
Field-Weighted Citation Impact
0.00

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article

Reduction of supervision for biomedical knowledge discovery

Christos Theodoropoulos, Andrei Catalin Coman, Marie‐Francine Moens, James Henderson
BMC Bioinformatics
Biomedical Text Mining and Ontologies
article

Reduction of supervision for biomedical knowledge discovery

Christos Theodoropoulos, Andrei Catalin Coman, Marie‐Francine Moens, James Henderson
article en

Abstract

Our approach tackles a central issue in knowledge discovery: balancing performance with minimal supervision which is crucial to adapting models to varied and changing domains. This study also investigates the use of pointwise binary classification techniques within a weakly supervised framework for knowledge discovery. By gradually decreasing supervision, we assess the robustness of these techniques in handling noisy labels, revealing their capability to shift from weakly supervised to entirely unsupervised scenarios. Comprehensive benchmarking offers insights into the effectiveness of these techniques, examining how unsupervised methods can reliably capture complex relationships in biomedical texts. These results suggest an encouraging direction toward scalable, adaptable knowledge discovery systems, representing progress in creating data-efficient methodologies for extracting useful insights when annotated data is limited.

BMC BioinformaticsVol. 26(1)
École Polytechnique Fédérale de Lausanne (CH), Idiap Research Institute (CH), KU Leuven (BE)
National Science Foundation, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, Fonds Wetenschappelijk Onderzoek, Vlaamse regering
Openalex Percentile: Top 80%
Biomedical Text Mining and Ontologies
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