Gold/Prussian Blue-Based Nanocomposites with Dual Nanozyme Activities Exert a Synergistic Effect of Starvation Therapy and Sonodynamic Therapy in the Treatment of Liver Cancer
An intelligent composite nanomaterial was successfully developed, combining starvation therapy and sonodynamic therapy to significantly enhance the treatment of liver cancer. The Au/PB-Ce6-HA nanozyme system demonstrated excellent synergy in both in vitro and in vivo settings, offering a promising strategy for cancer therapy.
Authors
- Tengyue Zhao
- Chengzhi Song
- Yefei Yang (ORCID: https://orcid.org/0000-0002-0617-4162)
- Yurong Hu (ORCID: https://orcid.org/0000-0002-0354-7939)
- Shaofeng Duan (ORCID: https://orcid.org/0000-0003-2151-082X)
- Shengnan Huang (ORCID: https://orcid.org/0000-0003-2566-4324)
- Wanyi Chen (ORCID: https://orcid.org/0009-0000-8150-2624)
- Chunming Li (ORCID: https://orcid.org/0000-0001-8504-4800)
- Lixian Li (ORCID: https://orcid.org/0000-0003-1931-8281)
- Xiaogang Hu (ORCID: https://orcid.org/0000-0002-0253-5418)
- Zhiwei Yao
Institutions
- Chongqing University (CN)
- Peking University (CN)
- Zhengzhou University (CN)
- Henan University of Engineering (CN)
- Chongqing Cancer Hospital (CN)
- First Affiliated Hospital of Henan University (CN)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2025-09-01
- DOI
- https://doi.org/10.2147/ijn.s490343
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Chongqing
- Natural Science Foundation of Henan Province