Langerhans cell histiocytosis successfully treated with combination of thalidomide and corticosteroid

There is no gold standard of treatment for Langerhans cell histiocytosis (LCH) in adults.Around 50% of patients with LCH were unresponsive to the standard therapy and no standard regimen was recommended for patients with refractory LCH.A combination of thalidomide and corticosteroid may be a therapeutic option in patients with LCH.

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Publication Details

Journal
European Journal of Case Reports in Internal Medicine
Published
2025-09-01
DOI
https://doi.org/10.12890/2025_005534
Primary Topic
Histiocytic Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Langerhans cell histiocytosis successfully treated with combination of thalidomide and corticosteroid

Candra Kurniawan, Nadia Ayu Mulansari, Abdul Muthalib
European Journal of Case Reports in Internal Medicine
Histiocytic Disorders and Treatments
article

Langerhans cell histiocytosis successfully treated with combination of thalidomide and corticosteroid

Candra Kurniawan, Nadia Ayu Mulansari, Abdul Muthalib
article en

Abstract

There is no gold standard of treatment for Langerhans cell histiocytosis (LCH) in adults.Around 50% of patients with LCH were unresponsive to the standard therapy and no standard regimen was recommended for patients with refractory LCH.A combination of thalidomide and corticosteroid may be a therapeutic option in patients with LCH.

European Journal of Case Reports in Internal MedicineVol. 12(10)
University of Indonesia (ID)
Openalex Percentile: Top 71%
Histiocytic Disorders and Treatments
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