Immediate Motor Control Enhancement via Pallidothalamic Tract (<scp>PTT</scp>) Circuit Ablation: A Dual‐Target <scp>MR</scp>‐Guided Focused Ultrasound Approach for Tremor‐Dominant Parkinson's Disease

These findings highlight the immediate therapeutic impact of PTT lesioning following VIM lesioning in the same treatment session, reinforcing its role as a crucial add-on target for managing refractory PD symptoms beyond tremor. This dtMRgFUS approach offers a more comprehensive motor benefit, particularly for patients with rigidity.

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Publication Details

Journal
European Journal of Neurology
Published
2025-09-01
DOI
https://doi.org/10.1111/ene.70345
Citations
3
Primary Topic
Neurological disorders and treatments
Type
article
Field-Weighted Citation Impact
4.17

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article

Immediate Motor Control Enhancement via Pallidothalamic Tract (PTT) Circuit Ablation: A Dual‐Target MR‐Guided Focused Ultrasound Approach for Tremor‐Dominant Parkinson's Disease

Chon‐Haw Tsai, Ming‐Kuei Lu, Yu Aoh, Chun‐Ming Chen et al.
3 citations
European Journal of Neurology
Neurological disorders and treatments
4.17
article

Immediate Motor Control Enhancement via Pallidothalamic Tract (PTT) Circuit Ablation: A Dual‐Target MR‐Guided Focused Ultrasound Approach for Tremor‐Dominant Parkinson's Disease

Chon‐Haw Tsai, Ming‐Kuei Lu, Yu Aoh, Chun‐Ming Chen, Jui‐Cheng Chen, Yu‐Kai Cheng
article en
3 citations

Abstract

These findings highlight the immediate therapeutic impact of PTT lesioning following VIM lesioning in the same treatment session, reinforcing its role as a crucial add-on target for managing refractory PD symptoms beyond tremor. This dtMRgFUS approach offers a more comprehensive motor benefit, particularly for patients with rigidity.

European Journal of NeurologyVol. 32(9)
China Medical University (TW), China Medical University Hospital (TW)
Ministry of Science and Technology, China Medical University Hospital, Ministry of Science and Technology, Taiwan, National Tsing Hua University, China Medical University, National Science and Technology Council, Division of Materials Research
Openalex Percentile: Top 5%
Neurological disorders and treatments
4.17
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