Euxanthone Inhibits Hepatocellular Carcinoma Progression by Targeting the miR-199a-5p/E2F3 Regulatory Axis

Taken together, euxanthone exerts antiproliferative effects on HCC cells via the miR-199a-5p-E2F3 axis and inhibits cell migration. These findings support its potential as a therapeutic agent for HCC, highlighting the need for further investigation into its clinical applications.

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Publication Details

Journal
Anti-Cancer Agents in Medicinal Chemistry
Published
2025-08-28
DOI
https://doi.org/10.2174/0118715206392043250805112033
Primary Topic
Cancer Mechanisms and Therapy
Type
article
Field-Weighted Citation Impact
0.00
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article

Euxanthone Inhibits Hepatocellular Carcinoma Progression by Targeting the miR-199a-5p/E2F3 Regulatory Axis

Ahmed Abdullah Al Awadh
Anti-Cancer Agents in Medicinal Chemistry
Cancer Mechanisms and Therapy
article

Euxanthone Inhibits Hepatocellular Carcinoma Progression by Targeting the miR-199a-5p/E2F3 Regulatory Axis

Ahmed Abdullah Al Awadh
article en

Abstract

Taken together, euxanthone exerts antiproliferative effects on HCC cells via the miR-199a-5p-E2F3 axis and inhibits cell migration. These findings support its potential as a therapeutic agent for HCC, highlighting the need for further investigation into its clinical applications.

Anti-Cancer Agents in Medicinal ChemistryVol. 25
Najran University (SA)
Openalex Percentile: Top 67%
Cancer Mechanisms and Therapy
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Euxanthone Inhibits Hepatocellular Carcinoma Progression by Targeting the miR-199a-5p/E2F3 Regulatory Axis — Ahmed Abdullah Al Awadh · Anti-Cancer Agents in Medicinal Chemistry (2025) | TGRS Research Map | TGRS