Clinical characteristics, pregnancy outcomes, and neonatal effects of cytomegalovirus infection in pregnant women in Liuzhou city, North central Guangxi of Southern China: a retrospective study from 2018 to 2024
Diagnosis of primary CMV infection during pregnancy is of critical importance. Current guidelines recommend implementing CMV serological screening during the first trimester, with subsequent CMV IgG avidity testing when CMV IgG antibodies are detected. Maternal CMV infection during the second and third trimesters may lead to fetal complications, including ventriculomegaly, FGR and fetal hydrops. Congenital CMV (cCMV) infection predominantly manifests with sensorineural hearing loss (SNHL) and cerebral palsy. It is essential to screen all neonates from CMV-infected pregnant women for CMV DNA and provide mandatory 5-year follow-up for symptomatic cCMV children.
Authors
- Qingyan Zhong
- Jiaolian Ya
- Ning Tang (ORCID: https://orcid.org/0000-0003-2185-4737)
- Weiyou Lv
- Xiaoni Wei
- Lizhu Chen (ORCID: https://orcid.org/0000-0002-9881-2976)
- Hui Chen (ORCID: https://orcid.org/0000-0001-6883-3752)
- Ling Zhang (ORCID: https://orcid.org/0000-0002-9961-2079)
- Pengfei Cai (ORCID: https://orcid.org/0000-0002-3870-341X)
- Bailing Liu (ORCID: https://orcid.org/0000-0001-7825-5263)
- Xiangrong Tang (ORCID: https://orcid.org/0000-0002-6022-2583)
- Guang Cheng (ORCID: https://orcid.org/0000-0002-5287-0804)
- Yuanxiu Li
- Qingzhou Lai
- Lifang Zhang
- Dejian Yuan (ORCID: https://orcid.org/0000-0001-9884-2158)
Institutions
- Liuzhou Maternal and Child Health Hospital (CN)
Publication Details
- Journal
- BMC Pregnancy and Childbirth
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1186/s12884-025-08083-0
- Primary Topic
- Cytomegalovirus and herpesvirus research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Guangxi Zhuang Autonomous Region
- Innovative Research Group Project of the National Natural Science Foundation of China
- National Natural Science Foundation of China
- Guangxi Key Research and Development Program