Mammalian conservation of endogenous G-quadruplex reveals their associations with complex traits
Our study highlights the important regulatory functions and close association with complex human traits of human eG4s that are highly conserved in the mammalian lineage.
Authors
- Zhen‐Xia Chen (ORCID: https://orcid.org/0000-0003-0474-902X)
- Sheng Hu Qian (ORCID: https://orcid.org/0000-0002-6194-3876)
- Wen Zhang (ORCID: https://orcid.org/0000-0001-5221-2628)
- Ziyan Wang (ORCID: https://orcid.org/0000-0003-2017-1993)
- Conghui Li (ORCID: https://orcid.org/0000-0002-4991-4474)
- Ze-Hao Zhang (ORCID: https://orcid.org/0000-0002-2190-491X)
Institutions
- Huazhong Agricultural University (CN)
- Wuhan University (CN)
- Hubei Academy of Agricultural Sciences (CN)
Publication Details
- Journal
- Genome biology
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1186/s13059-025-03750-z
- Citations
- 2
- Primary Topic
- RNA Interference and Gene Delivery
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- Francis Crick Institute
- National Natural Science Foundation of China
- Wuhan University
- National Key Research and Development Program of China
- Fundamental Research Funds for the Central Universities