Neuroprotective effect of Urolithin A via downregulating VDAC1-mediated autophagy in Alzheimer's disease
These findings demonstrated that UA down-regulated VDAC1 played a key neuroprotective role on AD by inhibiting the PI3K/AKT/mTOR pathway and activating the AMPK pathway to promote autophagy.
Authors
- Suteera Narakornsak
- Chun Shi
- Nirmala Chandralega Kampan (ORCID: https://orcid.org/0000-0003-1417-192X)
- Bensi Zhang (ORCID: https://orcid.org/0000-0002-6865-1972)
- Manussabhorn Phatsara (ORCID: https://orcid.org/0000-0002-9784-8280)
- Rungusa Pantan (ORCID: https://orcid.org/0000-0002-8277-7459)
- Waleephan Treebupachatsakul
- Xiujun Zhang (ORCID: https://orcid.org/0000-0003-0469-740X)
Institutions
- Chiang Mai University (TH)
- Dali University (CN)
Publication Details
- Journal
- Acta Histochemica
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1016/j.acthis.2025.152290
- Citations
- 1
- Primary Topic
- Pomegranate: compositions and health benefits
- Type
- article
- Field-Weighted Citation Impact
- 1.12