Supplementary Figure S5 from GPSai: A Clinically Validated AI Tool for Tissue of Origin Prediction during Routine Tumor Profiling
<p>Threshold selection for GPSai. The dashed line at 0.55 indicates the threshold determined to optimize both CUP call rate (green line) and hierarchical positive predictive value (hPPV, blue line) for metastatic cases. A GPS score ≥0.55 indicates high confidence in the tumor type prediction and will be included on the molecular report.</p>
Authors
- Jennifer R. Ribeiro (ORCID: https://orcid.org/0000-0002-1685-8568)
- Patricia Pittman
- Anthony Helmstetter
- Hassan Ghani
- Jaclyn F. Hechtman (ORCID: https://orcid.org/0000-0003-2645-0985)
- Rebecca Feldman (ORCID: https://orcid.org/0000-0003-4502-1473)
- Ari M. Vanderwalde (ORCID: https://orcid.org/0000-0002-6842-2563)
- Elena Florento
- Milan M. Radovich (ORCID: https://orcid.org/0000-0001-9667-156X)
- Jeffrey Swensen (ORCID: https://orcid.org/0000-0002-8204-4220)
- Matthew James Oberley (ORCID: https://orcid.org/0000-0001-6419-2513)
- Jim Abraham (ORCID: https://orcid.org/0000-0001-5038-1735)
- Casey Bales (ORCID: https://orcid.org/0000-0002-1016-6042)
- George W. Sledge (ORCID: https://orcid.org/0000-0003-0297-0775)
- Todd Maney
- Farah Abdulla (ORCID: https://orcid.org/0000-0002-3455-7566)
- David B. Spetzler (ORCID: https://orcid.org/0000-0002-9531-0970)
- Myra M. George
- David Bryant
- Stephanie Rock (ORCID: https://orcid.org/0000-0001-5700-6954)
Publication Details
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1158/2767-9764.30021992
- Primary Topic
- Radiomics and Machine Learning in Medical Imaging
- Type
- article
- Field-Weighted Citation Impact
- 0.00