PREGNANCY AND VON WILLEBRAND DISEASE: A MODERN APPROACH TO RISK, MONITORING, AND PROGNOSIS

Von Willebrand disease (VWD), recognized as the most prevalent hereditary bleeding disorder, poses substantial challenges in the management of pregnancy for both the patient and the medical team. As gestation advances, physiological alterations in coagulation factors modify the hemostatic equilibrium; nevertheless, this intrinsic adaptation does not invariably confer sufficient safeguarding against hemorrhagic threats, particularly during the postpartum period. This article delineates the fundamental tenets of customized management, from biological surveillance to therapeutic decision-making, emphasizing the critical significance of multidisciplinary collaboration. The objective is to guarantee secure and personalized care for affected women, predicated on their hematological profile and obstetric circumstances.