MORPHOFUNCTIONAL SYSTEM CONDUIT-ARTERY IN ACUTE CORONARY SYNDROME

Highlights The analytical review proposes to consider the morphofunctional conduit-artery system in the context of acute coronary syndrome, which is one of the leading problems of modern angiology. Based on the data of currently available fundamental and clinical studies, possible pathophysiological scenarios are shown that potentially occur in the elements of this system. Abstract The review considers the autobionic morphofunctional conduit-artery system, formed surgically during coronary artery bypass grafting, including such elements as the afferent (conduit) and receiving (coronary artery) vessels, as well as blood, from the position of its functioning in conditions of an acute coronary event. For a fundamental understanding of the current status of open myocardial revascularization, which has many unresolved issues, including the timing of surgery, volume, drug therapy, etc., various pathophysiological aspects reflecting the response of the system and its elements to a vascular catastrophe are shown. In this context, new horizons are opened for further study of surgical revascularization, which will help optimize the approach to this type of treatment in patients with acute coronary syndrome.