Clinical evaluation of the efficacy of orocheck tablets as an adjunct to non-surgical periodontal therapy in patients with mild to moderate periodontitis: A randomized controlled clinical trial

ABSTRACT Aim: The study aims to evaluate the efficacy of probiotic chewable tablets (orocheck) containing Lactobacillus paracasei GMNL-33 along with non-surgical periodontal therapy on clinical parameters of mild to moderate chronic periodontitis (CP) patients. Methodology: This is a randomized controlled study conducted on 80 patients in the Department of Periodontics and Oral Implantology at Lenora Institute of Dental Sciences in Rajanagaram from January 2023 to April 2023. Patients were selected by toss-a-coin method; patients received scaling and root planing (SRP) and were randomly allocated into two treatment groups: Groups 1 and 2. Group 2 received chewable probiotic tablets (orocheck). All patients were asked to abstain from using other probiotic and antibiotic medication during the study period. Clinical parameters (plaque index, gingival index, probing pocket depth, clinical attachment level) are evaluated at baseline, 1 month, and 3 months in both groups. Statistical Analysis: Statistical analysis was conducted utilizing IBM Statistical Package for the Social Sciences software (SPSS) Version 23.0. Results: On intergroup analysis, statistically significant improvement in clinical parameters was observed in Group 2(SRP + PROBIOTIC) compared to Group 1 (SRP ALONE). Conclusion: The results indicated that oral administration of L. paracasei could be a useful adjunct to SRP in mild to moderate periodontitis.

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Journal
Journal of Dr. YSR University of Health Sciences.
Published
2025-01-01
DOI
https://doi.org/10.4103/jdrntruhs.jdrntruhs_158_23
Primary Topic
Oral microbiology and periodontitis research
Type
article
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article

Clinical evaluation of the efficacy of orocheck tablets as an adjunct to non-surgical periodontal therapy in patients with mild to moderate periodontitis: A randomized controlled clinical trial

Maddula Y. S. L. N. V. Amruthavalli, Nalamati Shiva Keerthi, Kalluri Yasasvi, Pabbineedi Sai Satya Sri et al.
Journal of Dr. YSR University of Health Sciences.
Oral microbiology and periodontitis research
article

Clinical evaluation of the efficacy of orocheck tablets as an adjunct to non-surgical periodontal therapy in patients with mild to moderate periodontitis: A randomized controlled clinical trial

Maddula Y. S. L. N. V. Amruthavalli, Nalamati Shiva Keerthi, Kalluri Yasasvi, Pabbineedi Sai Satya Sri, Dalli Bharath Simha Reddy, Gathram Prathyusha
article en

Abstract

ABSTRACT Aim: The study aims to evaluate the efficacy of probiotic chewable tablets (orocheck) containing Lactobacillus paracasei GMNL-33 along with non-surgical periodontal therapy on clinical parameters of mild to moderate chronic periodontitis (CP) patients. Methodology: This is a randomized controlled study conducted on 80 patients in the Department of Periodontics and Oral Implantology at Lenora Institute of Dental Sciences in Rajanagaram from January 2023 to April 2023. Patients were selected by toss-a-coin method; patients received scaling and root planing (SRP) and were randomly allocated into two treatment groups: Groups 1 and 2. Group 2 received chewable probiotic tablets (orocheck). All patients were asked to abstain from using other probiotic and antibiotic medication during the study period. Clinical parameters (plaque index, gingival index, probing pocket depth, clinical attachment level) are evaluated at baseline, 1 month, and 3 months in both groups. Statistical Analysis: Statistical analysis was conducted utilizing IBM Statistical Package for the Social Sciences software (SPSS) Version 23.0. Results: On intergroup analysis, statistically significant improvement in clinical parameters was observed in Group 2(SRP + PROBIOTIC) compared to Group 1 (SRP ALONE). Conclusion: The results indicated that oral administration of L. paracasei could be a useful adjunct to SRP in mild to moderate periodontitis.

Journal of Dr. YSR University of Health Sciences.Vol. 14(1)
Kamineni Institute of Dental Sciences (IN)
Openalex Percentile: Top 75%
Oral microbiology and periodontitis research
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