Cognitive effort devaluation and the salience network: a computational model of amotivation in depression

Our findings demonstrate amotivation is specifically associated with cognitive effort devaluation in a cost-benefit analysis incorporating loss aversion, incentive learning, temporal discounting, and cognitive effort discounting. Modulation of effort valuation via the AIC-aMCC network suggests a potential treatment target.

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Publication Details

Journal
Frontiers in Psychiatry
Published
2025-09-01
DOI
https://doi.org/10.3389/fpsyt.2025.1581802
Primary Topic
Mental Health Research Topics
Type
article
Field-Weighted Citation Impact
0.00

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article

Cognitive effort devaluation and the salience network: a computational model of amotivation in depression

Kyungun Jhung, Chuan-Shun Lee, Il Ho Park
Frontiers in Psychiatry
Mental Health Research Topics
article

Cognitive effort devaluation and the salience network: a computational model of amotivation in depression

Kyungun Jhung, Chuan-Shun Lee, Il Ho Park
article en

Abstract

Our findings demonstrate amotivation is specifically associated with cognitive effort devaluation in a cost-benefit analysis incorporating loss aversion, incentive learning, temporal discounting, and cognitive effort discounting. Modulation of effort valuation via the AIC-aMCC network suggests a potential treatment target.

Frontiers in PsychiatryVol. 16
Catholic Kwandong University International St. Mary's Hospital (KR), Incheon Catholic University (KR), Catholic Kwandong University (KR)
National Research Foundation, National Research Foundation of Korea
Openalex Percentile: Top 76%
Mental Health Research Topics
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