The prevalence of genetic variants of the Mas-related G-protein-coupled receptor X2 in patients does not explain perioperative hypersensitivity reactions to neuromuscular blocking agents
SNPs detected within the protein coding sequence of the MRGPRX2 gene were not risk factor in NMBA-induced POH, regardless of the clinical characteristics of the patients and the causative drug in question.
Authors
- Grzegorz Porębski (ORCID: https://orcid.org/0000-0002-6146-0188)
- Ana Koren (ORCID: https://orcid.org/0000-0002-9671-1645)
- Wojciech Dyga (ORCID: https://orcid.org/0000-0002-5689-4803)
- Lenka Sedláčková (ORCID: https://orcid.org/0000-0003-1339-9914)
- Joanna Glück (ORCID: https://orcid.org/0000-0001-6339-9053)
- Adriana Šrotová
- Alicja Dziadowiec (ORCID: https://orcid.org/0000-0002-9675-7790)
- Mateusz Kwitniewski (ORCID: https://orcid.org/0000-0002-2743-6934)
- Peter Kopač (ORCID: https://orcid.org/0000-0001-7261-6689)
- Hubert Rybka (ORCID: https://orcid.org/0009-0007-1461-1346)
- Radoslaw Kitel
Institutions
- Jagiellonian University (PL)
- University of Ljubljana (SI)
- Medical University of Silesia (PL)
- University of Agriculture in Krakow (PL)
- University Clinic of Pulmonary and Allergic Diseases Golnik (SI)
- University Hospital Hradec Králové (CZ)
- Krakow Cardiovascular Research Institute (PL)
- Gennet (CZ)
- University of Silesia in Katowice (PL)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-09-01
- DOI
- https://doi.org/10.3389/fphar.2025.1655722
- Citations
- 1
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.16