Pembrolizumab in the treatment of non-small cell lung cancer—experiences from clinical practice

Our findings confirm the clinical benefit of pembrolizumab in a real-world setting, despite lower ORR compared to clinical trial data. However, the prognosis remains guarded due to the advanced stage and comorbidities of the population. Further investigation is warranted to optimize patient selection and treatment strategies.

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Publication Details

Journal
Frontiers in Medicine
Published
2025-09-01
DOI
https://doi.org/10.3389/fmed.2025.1635626
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
0.00
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article

Pembrolizumab in the treatment of non-small cell lung cancer—experiences from clinical practice

Marko Novakovic, Mirko Turic, Lora Novaković Lacković, Мirko Stanetić et al.
Frontiers in Medicine
Cancer Immunotherapy and Biomarkers
article

Pembrolizumab in the treatment of non-small cell lung cancer—experiences from clinical practice

Marko Novakovic, Mirko Turic, Lora Novaković Lacković, Мirko Stanetić, Marija Tomić, Aleksandra Kajkut, Teodora Macinkovic, Ranko Glamocak
article en

Abstract

Our findings confirm the clinical benefit of pembrolizumab in a real-world setting, despite lower ORR compared to clinical trial data. However, the prognosis remains guarded due to the advanced stage and comorbidities of the population. Further investigation is warranted to optimize patient selection and treatment strategies.

Frontiers in MedicineVol. 12
University of Banja Luka (BA), University clinical center of Republika Srpska (BA)
Openalex Percentile: Top 68%
Cancer Immunotherapy and Biomarkers
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