Rational design of an epitope-centric vaccine against Pseudomonas aeruginosa using pangenomic insights and immunoinformatics approach

The POA_V_RS09 vaccine candidate exhibited excellent stability, immunogenic potential, and expression efficiency, making it a promising candidate for combating <i>P. aeruginosa</i> infections. This study provides a strong foundation for developing effective therapeutic strategies to address the growing issue of antimicrobial resistance in <i>P. aeruginosa</i>. More experimental validation is needed to verify its effectiveness in preclinical and clinical environments.