Spoligotyping-based molecular typing of Mycobacterium tuberculosis complex isolated from Metahara sugar factory workers in Central Ethiopia

The high clustering rate observed may suggest recent transmission; however, this must be interpreted cautiously due to the limited discriminatory power of spoligotyping, which may overestimate clustering and underestimate diversity. This underscores the need for targeted TB control strategies informed by enhanced molecular surveillance.

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Publication Details

Journal
Frontiers in Medicine
Published
2025-09-01
DOI
https://doi.org/10.3389/fmed.2025.1641535
Primary Topic
Tuberculosis Research and Epidemiology
Type
article
Field-Weighted Citation Impact
0.00
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article

Spoligotyping-based molecular typing of Mycobacterium tuberculosis complex isolated from Metahara sugar factory workers in Central Ethiopia

Aboma Zewude, Hazim O. Khalifa, Temesgen Mohammed, Tilahun Bogale et al.
Frontiers in Medicine
Tuberculosis Research and Epidemiology
article

Spoligotyping-based molecular typing of Mycobacterium tuberculosis complex isolated from Metahara sugar factory workers in Central Ethiopia

Aboma Zewude, Hazim O. Khalifa, Temesgen Mohammed, Tilahun Bogale, Gobena Ameni
article en

Abstract

The high clustering rate observed may suggest recent transmission; however, this must be interpreted cautiously due to the limited discriminatory power of spoligotyping, which may overestimate clustering and underestimate diversity. This underscores the need for targeted TB control strategies informed by enhanced molecular surveillance.

Frontiers in MedicineVol. 12
Kafrelsheikh University (EG), United Arab Emirates University (AE), Addis Ababa University (ET)
Openalex Percentile: Top 72%
Tuberculosis Research and Epidemiology
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