A mitochondrial ferroptosis-related gene signature predicts prognosis and immune landscape in colon cancer
This mitochondrial ferroptosis-based risk model represents a promising prognostic biomarker and may offer valuable insights for personalized treatment strategies in colon cancer management. P4HA1 facilitates the advancement of colorectal cancer, while its suppression diminishes the <i>in vitro</i> proliferation and migration of colorectal cancer cells.
Authors
- Hou Wang (ORCID: https://orcid.org/0000-0002-2066-1856)
Institutions
- Shanghai Jiao Tong University (CN)
- Ruijin Hospital (CN)
- Ningbo No. 2 Hospital (CN)
- Ningbo No.6 Hospital (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-09-01
- DOI
- https://doi.org/10.3389/fmed.2025.1614012
- Citations
- 1
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- National Natural Science Foundation of China