Simultaneous 13N-ammonia and gadolinium perfusion using integrated PET-MRI: diagnostic accuracy in coronary microvascular dysfunction

CFR measurements were concordant between MRI and <sup>13</sup>N-ammonia PET. For detecting significant CMD, CFR<sub>MRI</sub> and CFR<sub>PET</sub> demonstrated comparable and high accuracy. Nevertheless, MRI measurements of rest and stress MBF showed only poor to modest agreement to those obtained with <sup>13</sup>N-ammonia PET. Therefore, although quantitative MRI has clinical utility, further refinements are still required.

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Journal
Frontiers in Medicine
Published
2025-09-01
DOI
https://doi.org/10.3389/fmed.2025.1649175
Primary Topic
Cardiac Imaging and Diagnostics
Type
article
Field-Weighted Citation Impact
0.00

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article

Simultaneous 13N-ammonia and gadolinium perfusion using integrated PET-MRI: diagnostic accuracy in coronary microvascular dysfunction

丹 李, Xinai Wu, Runze Wen, Zhenheng Wei et al.
Frontiers in Medicine
Cardiac Imaging and Diagnostics
article

Simultaneous 13N-ammonia and gadolinium perfusion using integrated PET-MRI: diagnostic accuracy in coronary microvascular dysfunction

丹 李, Xinai Wu, Runze Wen, Zhenheng Wei, Bo Pan, Xingxing Zhu, Ming Ni, Xuemei Wang, Xue Meng, Qiyu Xie
article en

Abstract

CFR measurements were concordant between MRI and <sup>13</sup>N-ammonia PET. For detecting significant CMD, CFR<sub>MRI</sub> and CFR<sub>PET</sub> demonstrated comparable and high accuracy. Nevertheless, MRI measurements of rest and stress MBF showed only poor to modest agreement to those obtained with <sup>13</sup>N-ammonia PET. Therefore, although quantitative MRI has clinical utility, further refinements are still required.

Frontiers in MedicineVol. 12
University of Science and Technology of China (CN), Inner Mongolia Medical University (CN)
University of Science and Technology of China
Openalex Percentile: Top 68%
Cardiac Imaging and Diagnostics
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Simultaneous 13N-ammonia and gadolinium perfusion using integrated PET-MRI: diagnostic accuracy in coronary microvascular dysfunction — 丹 李, Xinai Wu, et al. · Frontiers in Medicine (2025) | TGRS Research Map | TGRS