Plasma total and donor-derived cell-free DNA predict survival in kidney transplant recipients
This study demonstrates potential prognostic utility of total cfDNA and fractional ddcfDNA in KTRs with allograft dysfunction. Incorporation of these biomarkers could enhance personalised care, beyond non-invasive detection of rejection.
Authors
- David A. Power (ORCID: https://orcid.org/0000-0003-3983-0581)
- John B. Whitlam (ORCID: https://orcid.org/0000-0003-2202-1462)
- Alison Graver (ORCID: https://orcid.org/0000-0001-7585-0403)
Institutions
- The University of Melbourne (AU)
- Victorian Clinical Genetics Services (AU)
- Murdoch Children's Research Institute (AU)
- Austin Health (AU)
Publication Details
- Journal
- Frontiers in Transplantation
- Published
- 2025-09-01
- DOI
- https://doi.org/10.3389/frtra.2025.1624291
- Primary Topic
- Renal Transplantation Outcomes and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00