A Case Report of Pre-infantile Tremor Syndrome Presenting with Wheeze-associated Lower Respiratory Infection

Infantile tremor syndrome (ITS) is a rare but significant clinical condition characterized by tremors, anemia, developmental delay, skin hyperpigmentation, and sparse hair, typically seen in infants and young children between 5 months and 3 years of age.Pre-ITS refers to the early phase of ITS, where all characteristic symptoms of ITS are present except for tremors.It is most commonly seen in developing countries with low socio-economic conditions.There is no exact cause known till date.Numerous etiological factors, including metabolic, nutritional, dietary, and infectious aspects have been proposed.This case report describes an unusual presentation of pre-ITS in an 11-month-old male child who presented with a wheeze-associated lower respiratory infection (LRI).The report highlights the importance of the detection of ITS in the early phase of pre-ITS and thereby, prevent the long-term complications associated with ITS.