Navigating Pregnancy with Stargardt\'s Disease: A Case Report

Stargardt disease is the most prevalent autosomal recessive genetic form of macular dystrophy in both adults and children, which is caused by the mutation of ABCA4 gene.Its onset is commonly noted in the first half of the second decade of life.Stargardt disease is classically characterized by progressive RPE atrophy, the presence of yellow spots around the macula and mid-periphery of the retina with progressive central vision loss.The genes involved can have multiple variances, hence, this genetic disorder might be a diagnostic and therapeutic challenge.This is a case report of a 32-year-old term pregnant female affected with Stargardt disease, presented with progressive vision loss.

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Publication Details

Journal
Journal of South Asian Federation of Obstetrics and Gynaecology
Published
2025-08-30
DOI
https://doi.org/10.5005/jp-journals-10006-2631
Primary Topic
Retinal Development and Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Navigating Pregnancy with Stargardt\'s Disease: A Case Report

Neema Acharya, Sandhya Pajai, Anubha Dande, Sachin Rathod
Journal of South Asian Federation of Obstetrics and Gynaecology
Retinal Development and Disorders
article

Navigating Pregnancy with Stargardt\'s Disease: A Case Report

Neema Acharya, Sandhya Pajai, Anubha Dande, Sachin Rathod
article en

Abstract

Stargardt disease is the most prevalent autosomal recessive genetic form of macular dystrophy in both adults and children, which is caused by the mutation of ABCA4 gene.Its onset is commonly noted in the first half of the second decade of life.Stargardt disease is classically characterized by progressive RPE atrophy, the presence of yellow spots around the macula and mid-periphery of the retina with progressive central vision loss.The genes involved can have multiple variances, hence, this genetic disorder might be a diagnostic and therapeutic challenge.This is a case report of a 32-year-old term pregnant female affected with Stargardt disease, presented with progressive vision loss.

Journal of South Asian Federation of Obstetrics and GynaecologyVol. 17(4)
Openalex Percentile: Top 80%
Retinal Development and Disorders
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