Rapid and Efficient Synthesis of Pyran‐Annulated Kojic Acid Derivatives Catalyzed by Piperidinium Borate, a Conjugate Organic Base

ABSTRACT This study describes an effective method for synthesizing derivatives using piperidinium borate, a conjugate organic base catalyst. The methodology was tested with various aromatic aldehydes, substituted aromatic aldehydes, and aliphatic aldehydes with malononitrile and Kojic acid in EtOH: Water (1:1) as a greener solvent. The recovery of the catalyst from the aqueous layer was established for five cycles without loss of catalytic activity. This approach offers various benefits to synthesized pyran‐annulated heterocycles, such as smooth reaction conditions, shorter reaction time, easy availability of raw materials, and excellent product yield.