LUNG DAMAGE IN TOXIC SHOCK SYNDROME CAUSED BY HEMOLYTIC STREPTOCOCCUS GROUP A (a clinical case in pediatric practice)

Aim: to analyze the clinical and paraclinical features of lesions of the cardiovascular and respiratory systems caused by S. pyogenes, using the clinical case example. Materials and methods. In the infectious unit of anesthesiology and intensive care of the Chernivtsi Regional Children's Hospital, a boy was treated under our supervision and suffered from community-acquired pneumonia and signs of toxic shock syndrome, which developed on the background of a probable streptococcal infection case. The patient's examination and treatment were carried out in compliance with the basic bioethical provisions of the Council of Europe Convention on Human Rights and Biomedicine, the Declaration of Helsinki of the World Medical Association on the ethical principles of conducting scientific medical research involving human subjects, as well as in accordance with current national guidelines and local medical standarts. Results. The clinical case of streptococcal toxic shock syndrome caused by a probable streptococcal infection clearly demonstrates the relevance of this problem in pediatric practice. In the clinical case the severity of the child's condition is primarily caused by toxic shock syndrome, which was accompanied by hypotension and perfusion depression and progressive respiratory failure that required prolonged respiratory protection. In our opinion, the described clinical case can be considered as confirmation of the presence of streptococcal toxic shock syndrome in a child, caused by streptococcal infection with an infectious focus in the pulmonary parenchyma, and therapeutic measures should be comprehensive and multi-directional in order to bring the recovery time as quickly as possible. Conclusion. Taking into account the absence of any predictors of possible complications of streptococcal infection, this problem should be a warning for the practical pediatric staffs in terms of detecting in children with infectious dermatitis and/or respiratory infection such danger signs as respiratory, cardiovascular and perfusion disorders, increasing neurological symptoms for the purpose of rapid medical response and referral to a specialized department of a pediatric clinic for the specialized medical care.