The role of ZC3H13 in promoting M2 macrophage infiltration via m6A methylation in esophageal squamous cell carcinoma tumor progression
Our findings elucidate the connection between ZC3H13-mediated m6A modification and M2 macrophage infiltration in the ESCC-TME, resulting in M2 macrophage polarization and increased M2 macrophage infiltration.
Authors
- Junye Wang (ORCID: https://orcid.org/0000-0001-7968-7121)
- Chendi Xu
- Dachuan Liang
- Jie Yang (ORCID: https://orcid.org/0000-0001-5149-538X)
- Qihang Yan
- Yuzhen Zheng (ORCID: https://orcid.org/0000-0002-5260-6798)
- L. Gong (ORCID: https://orcid.org/0000-0003-0400-3180)
Institutions
- Sun Yat-sen University (CN)
- Sixth Affiliated Hospital of Sun Yat-sen University (CN)
- Sun Yat-sen University Cancer Center (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-09-01
- DOI
- https://doi.org/10.3389/fimmu.2025.1612041
- Citations
- 2
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.61