Soluble IL‐2 receptor levels support diagnosis of sarcoidosis‐like reaction in melanoma patients on immunotherapy – a diagnostic algorithm based on a single center retrospective study
In melanoma patients receiving ICI, DISR is common. Histological confirmation through mediastinoscopy or pulmonary wedge resection offers the highest diagnostic accuracy. When histology is not available, sIL2R levels can aid diagnosis. We propose an algorithm to distinguish DISR from tumor progression.
Authors
- Philipp Gussek
- Maxime Ablefoni (ORCID: https://orcid.org/0000-0003-3696-1471)
- Julia Mentzel (ORCID: https://orcid.org/0000-0002-7350-8767)
- Mirjana Ziemer (ORCID: https://orcid.org/0000-0001-6488-1917)
Institutions
- Helios Park-Klinikum Leipzig (DE)
- University Hospital Leipzig (DE)
- Leipzig University (DE)
Publication Details
- Journal
- JDDG Journal der Deutschen Dermatologischen Gesellschaft
- Published
- 2025-08-31
- DOI
- https://doi.org/10.1111/ddg.15727
- Primary Topic
- Sarcoidosis and Beryllium Toxicity Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00