Liquid-liquid phase separation in gastric cancer: identifying novel biomarkers and therapeutic targets through gene signature analysis
This study revealed the important role of LLPS in gastric cancer, and the constructed four-gene LLPS signature is expected to be a novel biomarker for prognostic assessment and treatment of gastric cancer. PSPC1 plays a key role in gastric cancer progression, and has the value of a potential therapeutic target.
Authors
- Xianhui Wen (ORCID: https://orcid.org/0000-0003-3661-9879)
- Miaomiao Cui
- Junhua Zhang (ORCID: https://orcid.org/0000-0001-7028-0632)
- Hai Huang (ORCID: https://orcid.org/0000-0002-7274-1460)
Institutions
- Central South University (CN)
- Guiyang Medical University (CN)
- Affiliated Hospital of Guizhou Medical University (CN)
- The First People's Hospital of Guiyang (CN)
- Third Xiangya Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-09-01
- DOI
- https://doi.org/10.3389/fimmu.2025.1620390
- Citations
- 1
- Primary Topic
- RNA Research and Splicing
- Type
- article
- Field-Weighted Citation Impact
- 0.81