A STUDY OF MASOOD’S AND MODIFIED MASOOD’S CYTOLOGICAL SCORING SYSTEM IN CYTOLOGICAL DIAGNOSIS OF BREAST LESIONS.

Fine Needle Aspiration Cytology (FNAC) is a reliable diagnostic tool to distinguish non-proliferative from proliferative breast lesions. The categorization of breast lesions is important in identifying  the women who are at risk for the development of breast cancer. So it is essential to segregate the breast lesions by using Masood's Scoring Index (MSI) and its modification (Modified Masood's scoring index; MMSI) based on cytomorphological examination further which helps in the prognosis and management. Objectives:  This study analyses the effectiveness of MMSI over MSI and asses the concordance between cytological scoring and histopathology of breast lesions. Methodology: A total of 105 patients were included in this prospective study done from June 2023 to May 2024 and the breast lesions were cytologically categorized by conventional and as per both MSI and MMSS criteria, followed by comparison to a histopathological examination, which was taken as a gold standard. Results: The age of the patients ranged from 24 to 82  years with a mean age of 42.3 ± 14.8 years. Predominently right-sided breast lesions were more common. The overall diagnostic accuracy of the cytological scoring was 98.7%, with 92.4% sensitivity and 100% specificity Conculsion: Cytological grading system based on MMSS allowed accurate diagnosis compared to the standard histopathological diagnosis. It is essential to differentiate non-proliferative lesions from proliferative lesions as the line of treatment and prognosis varies