The relationship between chronic pain and health-related quality of life: the mediating roles of frailty and depression in chronic disease patients
The study findings demonstrated that frailty and depression serve as significant chain mediators in the relationship between CP and diminished HRQoL. Measures should be taken to reduce the incidence and severity of CP in patients with chronic diseases, improve frailty and depression, and thus improve HRQoL.
Authors
- Huimin Cao (ORCID: https://orcid.org/0000-0001-7834-0409)
- Ping Dong (ORCID: https://orcid.org/0009-0009-5546-4965)
- Xianqi Zhang (ORCID: https://orcid.org/0000-0002-4500-9610)
- Wenqiang Yin (ORCID: https://orcid.org/0000-0001-7284-8359)
- Xiaona Li (ORCID: https://orcid.org/0009-0000-1596-5348)
- Kui Sun (ORCID: https://orcid.org/0009-0006-9923-4668)
- Dongping Ma
- Min Gao (ORCID: https://orcid.org/0000-0003-0553-1153)
- Haoqi Li
- Zhongming Chen (ORCID: https://orcid.org/0000-0002-9378-6676)
- Y T Shi
- Mengyuan Xu
- Ziyuan Li
- Xianglan Zhuge
Institutions
- Weifang Medical University (CN)
- Weifang People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Public Health
- Published
- 2025-09-01
- DOI
- https://doi.org/10.3389/fpubh.2025.1658008
- Citations
- 1
- Primary Topic
- Health Systems, Economic Evaluations, Quality of Life
- Type
- article
- Field-Weighted Citation Impact
- 3.13
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province