Long-Term Prognostic Value and Analytical Parameters of the Next-Generation Sequencing-Based Multigene Assay in Hormone Receptor-Positive, HER2-Negative Breast Cancer
We validated the prognostic ability of an NGS-based assay to stratify HR-positive/HER2-negative breast cancers and predict the risk of distant recurrence, and confirmed the requirement for stringent QC criteria to ensure its prognostic ability.
Authors
- Sae Byul Lee (ORCID: https://orcid.org/0000-0002-3370-6937)
- Kyoung Un Park (ORCID: https://orcid.org/0000-0002-2402-7633)
- Wonshik Han (ORCID: https://orcid.org/0000-0001-7310-0764)
- Gyungyub Gong (ORCID: https://orcid.org/0000-0001-5743-0712)
- Jiwon Koh (ORCID: https://orcid.org/0000-0002-7687-6477)
- Jai Min Ryu (ORCID: https://orcid.org/0000-0001-5405-7385)
- Han‐Byoel Lee (ORCID: https://orcid.org/0000-0003-0152-575X)
- Hong‐Kyu Kim (ORCID: https://orcid.org/0000-0002-7606-3521)
- Eunhye Kang
- Sujin Oh
- Hee-Chul Shin (ORCID: https://orcid.org/0000-0001-6512-2218)
- Dong Seung Shin (ORCID: https://orcid.org/0000-0001-8915-8944)
- Hyun-Woo Lee (ORCID: https://orcid.org/0009-0003-7212-2162)
- Jiyoung Lee (ORCID: https://orcid.org/0000-0001-7717-8104)
- Hyunji Kim (ORCID: https://orcid.org/0000-0002-7706-5860)
- Hee Jin Lee (ORCID: https://orcid.org/0000-0002-4963-6603)
- Yunhee Choi (ORCID: https://orcid.org/0000-0002-6399-4618)
- Ho Eun Chang
Institutions
- Seoul National University (KR)
- Samsung Medical Center (KR)
- Seoul National University Hospital (KR)
- Seoul National University Bundang Hospital (KR)
- University of Ulsan (KR)
- Sungkyunkwan University (KR)
Publication Details
- Journal
- Cancer Research and Treatment
- Published
- 2025-09-01
- DOI
- https://doi.org/10.4143/crt.2025.701
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00