Prognostic Role of SOCS1 Mutations in Diffuse Large B-Cell Lymphoma
SOCS1 mutations, particularly those in the SOCS-BOX domain, are associated with improved prognosis in DLBCL. By promoting immune activation and inhibiting cellular metabolism, these mutations may not only serve as prognostic biomarkers but also provide insights into potential therapeutic avenues.
Authors
- Wei Xu (ORCID: https://orcid.org/0000-0003-4208-7477)
- Hao-Rui Shen (ORCID: https://orcid.org/0000-0003-4330-850X)
- Rui Gao (ORCID: https://orcid.org/0000-0002-0845-1370)
- Hua Wei (ORCID: https://orcid.org/0000-0001-5897-528X)
- Li Wang (ORCID: https://orcid.org/0000-0001-7692-5067)
- Xinyi Zhang (ORCID: https://orcid.org/0000-0002-3173-0589)
- Yue Li (ORCID: https://orcid.org/0000-0003-4547-064X)
- Xinyu Zhang (ORCID: https://orcid.org/0000-0002-8194-4518)
- Jianyong Li (ORCID: https://orcid.org/0000-0002-9931-4055)
- Hua Yin
- Yilin Kong (ORCID: https://orcid.org/0009-0006-6581-1244)
- Jia‐Zhu Wu
- Jin‐Hua Liang
- Tong‐Yao Xing
- Bihui Pan
Institutions
- Nanjing Medical University (CN)
Publication Details
- Journal
- Cancer Research and Treatment
- Published
- 2025-09-01
- DOI
- https://doi.org/10.4143/crt.2025.420
- Primary Topic
- Cytokine Signaling Pathways and Interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00