Single‐dose <i>Pasteurella multocida</i> and <i>Histophilus somni</i> autogenous vaccines administered at induction significantly improved feedlot cattle performance and profitability in Australia

Given the overall reduced BRD incidence during the study period, the observed results may be influenced by pathogen prevalence, vaccine dosage, timing, route of administration and environmental factors. While the single-dose vaccine improved subclinical disease outcomes and growth performance, further studies, including a two-dose vaccine trial, are required to assess the full potential of the anamnestic immune response.