Potential Survival Benefit of Adjuvant Chemotherapy in Stage <scp>IV</scp> Intrahepatic Cholangiocarcinoma: A Multicenter, Stage‐Stratified Analysis
Adjuvant chemotherapy was associated with improved survival in patients with resected stage IV ICC. Among available regimens, S-1 appeared to contribute to this benefit. These findings support the use of AC in advanced ICC and suggest that S-1 may play a potential role, warranting further prospective validation. Stage-specific treatment planning may be essential to optimize outcomes.
Authors
- Yusuke Yamamoto (ORCID: https://orcid.org/0000-0001-5292-7228)
- Haruki Mori (ORCID: https://orcid.org/0000-0001-9143-256X)
- Satoshi Yasuda (ORCID: https://orcid.org/0000-0003-4323-7422)
- Hiroji Shinkawa (ORCID: https://orcid.org/0000-0002-0164-2414)
- Masaki Kaibori (ORCID: https://orcid.org/0000-0002-0577-3921)
- Hisashi Kosaka (ORCID: https://orcid.org/0000-0002-2926-9973)
- Tsukasa Aihara (ORCID: https://orcid.org/0000-0003-1463-0073)
- Masaki Ueno (ORCID: https://orcid.org/0000-0001-6310-0795)
- Masahiko Kinoshita (ORCID: https://orcid.org/0000-0002-6716-6377)
- Koji Komeda
Institutions
- Kansai Medical University (JP)
- Shiga University of Medical Science (JP)
- Kyoto Prefectural University of Medicine (JP)
- Miwa Hospital (JP)
- Osaka Minami Medical Center (JP)
- Metropolitan University (VE)
- Hyogo Prefectural Nishinomiya Hospital (JP)
- Nara Medical University (JP)
- Osaka University of Pharmaceutical Sciences (JP)
Publication Details
- Journal
- Annals of Gastroenterological Surgery
- Published
- 2025-08-31
- DOI
- https://doi.org/10.1002/ags3.70087
- Primary Topic
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00