GLP-1 and GIP Changes after Sleeve Gastrectomy and Weight Regain in Adolescents. Do we need a Boost?
LSG produces sustained weight loss and metabolic benefits in adolescents. Incretin surges attenuate over time, particularly among those experiencing WR. A one-year course of semaglutide partially reversed WR, suggesting a potential adjunctive role for GLP-1 agonists in selected patients. Early hormonal differences warrant prospective research to clarify predictive value for weight regain.
Authors
- Sherif Shehata (ORCID: https://orcid.org/0000-0002-9733-006X)
- A. Elhaddad (ORCID: https://orcid.org/0000-0002-4119-0790)
- Mohamed Ali Shehata (ORCID: https://orcid.org/0000-0003-3913-1836)
- Ashraf El Attar
- M. A. Mansour (ORCID: https://orcid.org/0000-0003-1990-6542)
Institutions
- Tanta University (EG)
Publication Details
- Journal
- Obesity Surgery
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1007/s11695-025-08168-x
- Primary Topic
- Bariatric Surgery and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Tanta University